Research into conolidine has resulted in discovery of the opioid receptor in the body termed ACKR3/CXCR7. ACKR3 appears to be essentially the most sought after target for conolidine, which also disregards the opposite four classical opioid receptors(three). thank you.. A: There is limited data on contraindications among Conolidine and https://www.proleviate.com/post/conolidine-an-alternative-natural-pain-relief-to-replace-traditional-painkillers