Conolidine’s analgesic consequences stem from its interaction with non-opioid pain pathways. Compared with opioids, which bind to µ-opioid receptors within the central nervous system, conolidine modulates alternate molecular targets. A Science Advancements review observed that conolidine interacts While using the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide ... https://isconolidinearealpainreli53074.canariblogs.com/a-review-of-alternative-natural-pain-relief-to-replace-traditional-painkillers-52899637