Epidural clonidine utilized being an adjunct to regional anesthetics has 3 distinctive mechanisms of action. Initially, the stimulation of alpha-two-receptors while in the dorsal horn reduces pain transmission. Secondly, clonidine could potentially cause local vasoconstriction that limits vascular removal of local epidural anesthetics. : connected to, served by, or https://peteru605sme3.hyperionwiki.com/user