Not all patients with CLL have to have therapy. Inspite of all current improvements, the iwCLL nevertheless endorses watchful observation for individuals with asymptomatic disorder.86 This advice is based on at the least two randomized trials comparing observation to possibly chlorambucil monotherapy or fludarabine, cyclophosphamide and rituximab (FCR).103,104 Each trials https://letitiaz964ubi1.birderswiki.com/user