Many of the flavonoids inhibited 3βHSD2 and CYP17A1 noticeably, though the inhibition of downstream enzymes, CYP21A2 and CYP11B1, was the two substrate and flavonoid unique. The dihydrochalcones inhibited the activity of CYP21A2, but not that of CYP11B1. Although rutin, orientin and vitexin inhibited deoxycortisol conversion by CYP11B1 significantly, inhibition of http://htlnk.com/tea1